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Up Getting A Test While Self Isolating Ate . You are likely most infectious during these first 5 days. July 31, 2020, 1:56 pm pdt. Do I have to pay staff who are selfisolating? from s37564.pcdn.co Your local public health authority may advise you to quarantine or. To best detect infection, a negative antigen test should be repeated at least 48 hours apart (known as serial testing). You should not go to work,.